Congratulations to Rob Dowen, an iBGS fellow working in Shawn Ahmed’s lab, whose paper entitled “A microRNA program in the C. elegans hypodermis couples to intestinal mTORC2/PQM-1 signaling to modulate fat transport” was recently published in Genes and Development (Dowen RH, Breen PC, Tullius T, Conery AL, Ruvkun G (2016) Genes Dev. Jul 1.) and is accompanied by an Outlook article. The paper uncovered a new non-cell-autonomous input into the mTORC2 signaling pathway that modulates fatty acid metabolism. READ MORE >>
Congratulations to Biology undergraduates Karthika Kandala and Kirsten Adams, who received funding to work in the Greg Matera lab over the summer. Karthika received a “SURF Award” to study the application of tRNA intronic circular (tric)RNA technology, while Kirsten has funding from the “Chancellor’s Science Scholars Program” to study epigenetic regulation of gene expression.
Congratulations to Greg Matera, who was recently awarded an NIH R01 grant from NIGMS (National Institute of General Medical Sciences) entitled “In vivo models of small RNP biogenesis and Spinal Muscular Atrophy”. This grant provides $1.2M support over 4 years for the Matera lab to elucidate the molecular, cellular and developmental consequences of partial loss-of-function mutations in the Survival Motor Neurons gene, leading to a better understanding of the human neuromuscular disease, Spinal Muscular Atrophy.
Congratulations to Mike Meers of Greg Matera’s lab. Mike received a travel fellowship to share his research at the “2016 RNA Society Meeting” in Kyoto, Japan. Mike’s poster describes how mutation of the histone H3K36 residue affects gene expression. RNA 2016 >>