Congratulations to Greg Matera, who was recently awarded an NIH R01 grant from NIGMS (National Institute of General Medical Sciences) entitled “In vivo models of small RNP biogenesis and Spinal Muscular Atrophy”. This grant provides $1.2M support over 4 years for the Matera lab to elucidate the molecular, cellular and developmental consequences of partial loss-of-function mutations in the Survival Motor Neurons gene, leading to a better understanding of the human neuromuscular disease, Spinal Muscular Atrophy.
Congratulations to Mike Meers of Greg Matera’s lab. Mike received a travel fellowship to share his research at the “2016 RNA Society Meeting” in Kyoto, Japan. Mike’s poster describes how mutation of the histone H3K36 residue affects gene expression. RNA 2016 >>
Congratulations to Eric Garcia, Ying Wen, and Greg Matera for their paper published in RNA titled “Transcriptomic comparison of Drosophila snRNP biogenesis mutants reveals mutant-specific changes in pre-mRNA processing: implications for spinal muscular atrophy”. Along with former Matera lab member Kavita Praveen, this paper presents the results of multiple RNA-seq experiments in Drosophila mutants of small nuclear ribonucleoprotein (snRNP) biogenesis, which is an important cellular process. READ MORE >>
Congratulations to Casey Schmidt, John Noto, and Greg Matera for their paper published in Methods in Enzymology titled “A Method for Expressing and Imaging Abundant, Stable, Circular RNAs In Vivo Using tRNA Splicing”. Along with collaborator Grigory Filonov from Samie Jaffrey’s lab at Weill Cornell Medical College, the paper details a method to produce and image fluorescent circular RNAs using novel technology. READ MORE >>