Skip Navigation
Increase font size
Decrease font size

Daniel J. McKay

Assistant Professor, Biology Department and Genetics Department; Integrative Program for Biological and Genome Studies (iBGS)

Contact Information

Office: 3358 Genome Sciences Building
Email: dmckay1[at]
Office Phone: (919) 843-2064

McKay Lab Website


Department of Genetics
Integrative Program for Biological and Genome Studies (iBGS)

Research in the lab focuses on how a single genome gives rise to a variety of cell types and body parts during development. We use Drosophila as a model organism to investigate (1) how transcription factors access DNA to regulate complex patterns of gene expression, and (2) how post-translational modification of histones contributes to maintenance of gene expression programs over time. We combine genomic approaches (e.g. chromatin immunoprecipitation followed by high-throughput sequencing) with Drosophila genetics and transgenesis to address both of these questions. Defects in cell fate specification and maintenance of cell identity often occur in human diseases, including cancer. (website)