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Bob Goldstein

James L. Peacock III Distinguished Professor

Contact Information

Office: 616 Fordham Hall
Email: bobg[at]
Office Phone: (919) 843-8575
Lab Phone: (919) 843-8576

Goldstein Lab Website

Research Description

We are interested in understanding how cells develop into organisms. We love the nematode C. elegans, because it allows us to readily combine a great number of useful techniques, including techniques of cell biology, direct manipulation of cells, forward and reverse genetics, biochemistry, molecular biology, biophysics, and live imaging of cells and their dynamic, cytoskeletal components.

Current work in the lab addresses several fundamental questions in cell and developmental biology — how cells move to specific positions during development, how cells change shape, how intercellular signals act to polarize cells, and how the mitotic spindle is positioned in cells. We are also developing an obscure relative of C. elegans and Drosophila, a water bear, to study how such developmental mechanisms can evolve to produce organisms with different forms.