Congratulations to Lela Lackey (postdoc, Alain Laederach’s lab) for receiving a grant from “Alpha-1 Foundation” to study the effects of non-coding mutations on the expression of the Alpha-1-antitrypsin protein. Dr. Lackey will investigate novel variants in the UTRs of the messenger RNA coding for Alpha-1-antitrypsin protein that lower its expression and lead to a wide range of pathologies including liver cirrhosis and chronic obstructive pulmonary disease. The Alpha-1 Foundation promotes the research and the development of new therapies for improving the quality of life for those diagnosed with Alpha-1-antitrypsin deficiency. Read more about the foundation > >

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