The Copenhaver lab has published a collaborative paper in The Proceedings of the National Academy of Sciences entitled “DNA polymerase epsilon interacts with SUVH2/9 to repress the expression of genes associated with meiotic DSB hotspot in Arabidopsis” which shows that genes associated with DNA double strand breaks (DSBs) are silenced during meiosis by a subunit of DNA polymerase epsilon (POL2A) acting together with a SET domain protein (SUVH9). This work advances our understanding of how epigenetic mechanisms influence plant reproductive biology. The first author of the paper, Cong Wang, was co-advised by Drs. Copenhaver and Wang, and the second author, Jiyue Wang joined the Copenhaver lab as a postdoctoral associate.
https://doi.org/10.1073/pnas.2208441119